Induction of angiogenesis using VEGF releasing genipin-crosslinked electrospun gelatin mats
نویسندگان
چکیده
منابع مشابه
Genipin crosslinked gelatin nanofibers for tissue engineering.
summary The objective of this study was to enhance the mechanical and thermo-mechanical properties of electrospun gelatin nanofibers, while maintaining their good bioactivity. In this work, genipin was used as crosslinker to achieve this goal. Electrospun gelatin nanofibers were crosslinked with genipin vapor at room temperature for 0 h, 6 h, 12 h, 24 h, 48 h and 72 h. The morphologies of the c...
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Objective(s): To improve water stability of electrospun chitosan/ Polyethylene oxide (PEO) nanofibers, genipin, a biocompatible and nontoxic agent, was used to crosslink chitosan based nanofibers. Materials and Methods: Different amounts of genipin were added to the chitosan/PEO solutions, chitosan/PEO weight ratio 90/10 in 80 % acetic acid, and the solutions were then electrospun to form nano...
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Antimicrobial delivery has been advocated for guided tissue regeneration (GTR) or guided bone regeneration (GBR) therapies involving patients with aggressive or unresolved periodontitis/peri-implantitis. Electrospun chitosan membranes demonstrate several advantages over traditional GTR barrier membranes because they stimulate healing, mimic the topology of the extracellular matrix, and allow fo...
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Electrospun gelatin nanofibers attract great interest as a natural biomaterial for cartilage and tendon repair despite their high solubility in aqueous solution, which makes them also difficult to crosslink by means of chemical agents. In this work, we explore the efficiency of non-equilibrium atmospheric pressure plasma in stabilizing gelatin nanofibers. We demonstrate that plasma represents a...
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Reconstruction of large bone defects remains problematic in orthopedic and craniofacial clinical practice. Autografts are limited in supply and are associated with donor site morbidity while other materials show poor integration with the host's own bone. This lack of integration is often due to the absence of periosteum, the outer layer of bone that contains osteoprogenitor cells and is critica...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2013
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2013.06.040